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RNA · Regulatory biology · Artificial intelligence

Making human
biology readable.

Genesis advances drug discovery and development. Eigen Insights, Eigen Bio’s AI data business, brings biological expertise to three kinds of work:

Explore the science
RAS–RAF–MEK–ERK pathway

KRAS · RAF1 · MAP2K1 · MAPK1 · ELK1

Drag to rotate · Swipe sideways on touch

A curved three-dimensional network showing selected gene products in the MAPK, PI3K–AKT and WNT pathways. Choose a pathway to highlight its schematic associations. The selected genes are listed below the pathway buttons.

When the map is focused, arrow keys rotate, plus and minus zoom, Home resets the view, Space plays or pauses motion, and N explores the next gene. On touch screens, swipe horizontally to rotate; vertical swipes and pinch gestures remain available for page scrolling and browser zoom.

Illustrative human pathway map. Connections summarize pathway associations; geometry and motion carry no measured or causal meaning.

MAPK pathway reference
01
GenesisDrug discovery & development
02
Eigen InsightsEmergence · ORIGIN · Paladin
01 / GENESISDRUG DISCOVERY & DEVELOPMENT

From disease biology
to therapeutic programs.

We begin with the biology of disease. Genesis connects target hypotheses, drug assets and experimental validation to identify programs worth advancing.

Explore Genesis
01Disease biology

Define the state and unmet need.

02Target qualification

Examine the mechanism and evidence.

03Drug evaluation

Assess exposure, safety and development fit.

04Experimental validation

Test the assumptions that determine what advances.

Genesis / Pipeline

Our therapeutic pipeline.

Oncology programs built around assets with prior human PK data.

Evidence reviewed

EG-01

Prostate cancer

Treatment-persistent prostate cancer.

Current Eigen work
Asset evaluation & validation preparation
Next milestone
Finalize the validation protocol and confirm material access.
Rights status
Under evaluation
EG-02

Colorectal cancer

Treatment-persistent colorectal cancer.

Current Eigen work
Asset evaluation & validation preparation
Next milestone
Finalize the validation protocol and confirm material access.
Rights status
Under evaluation

Bars show prior asset development reaching Phase 1. Eigen’s current work in the proposed indications is asset evaluation and validation preparation.

View the pipeline chart
02 / EIGEN INSIGHTSDATA, PRODUCTS & SERVICES

Biological intelligence.
Put to work.

Eigen Insights brings together Emergence, ORIGIN and Paladin.

Explore Eigen Insights
A
For AI teams & data partners

Emergence

Expert-created tasks and evaluations grounded in diverse, growing proprietary biological data.

B
For researchers & biopharma

ORIGIN

Biological intelligence and scientific workflows for research and biopharma teams.

C
For patients & families

Paladin

Research and navigation support for patients and families facing serious disease.

Shared by Genesis and Eigen Insights

One foundation.
Two paths to value.

Biological data defines the question. Eigen-1 investigates regulatory programs. EigenField connects hypotheses with mechanistic evidence. Scientific review and validation determine the next step.

Regulatory foundation model

Eigen-1

Model transcriptomic states and investigate the programs that shape biological response.

Mechanistic knowledge graph

EigenField

Examine molecular relationships and the evidence supporting a biological hypothesis.

Model-derived hypotheses progress through scientific review and experimental validation. Data access and reuse follow the rights agreed for each project.

Explore the shared scienceExplore the therapeutic pipeline

Research

Examine the work.

Research & resources
01
Preprint · December 2025

A Biologically Grounded Structural Causal Model Enables cfRNA Specific In-Context Learning

02
Preprint · December 2025

cfRNA Codex: Integrated Cell-Free RNA Expression Atlas Across Diseases and States

03
Preprint · December 2025

Beyond Annotation: Leveraging Raw RNA-seq Reads via Foundation models for Multi-Cancer Early Detection

Contact Eigen Bio

Work with Eigen Bio.

Discuss a therapeutic program, an AI data project, an ORIGIN evaluation or a research partnership.

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